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Brief Introduction of GHRPs and GHRP-2

Since the late 1970s, on the basis of the structure of the met enkephalin, GHRPs was synthesized for the first time, people has synthesized several types of GHRPs. Although its structure is far different from met enkephalin structure, all can strongly stimulate the release of GH. GHRPs can promote GH to release, stimulate animal appetite, promote animal growth, and improve animal production performance and immune level in animals. The final product obtained from Escherichia coli fermentation after multistep purification.

GHRP 2 (growth hormone releasing peptide - 2 - peptide release of growth hormone) or Pralmorelin - growth hormones (growth hormone) in the case of sublingual and transbukkalny acceptance, exhibited excellent performance in the stimulus. GHRP-2, perhaps, develops from all existing growth hormone into unique and strongest enhancement (stimulation). GHRP-2 is an oligopeptide that passes through the blood vessels of the mouth and into the blood vessels of the liver. In the study, GHRP-2 stimulated the pituitary gland, resulting in an increase in growth hormone secretion of 7 to 15 times (other growth hormone stimulants, based on GABA and amino acid increases of no more than 2 times) from the initial 3 times).

GHRP-2 consists of six amino acids that are uniformly linked. This stimulant of growth hormone enters the peptide group that interacts with g-protein coupling receptors in the pituitary and hypothalamus and also activates glycoprotein receptors, which in turn lead to increased appetite. These peptides were first received from methotrexate at the end of the last century. Although in growth hormone releasing hormone (natural to stimulate the development of endogenous growth hormone bio activator), GHRP-2 has no structural similarity, in clinical trials, which showed similar effect on the pituitary gland.

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