24th Apr 2018
At the beginning of twentieth Century, Fischer first synthesized polypeptides with specific sequences.
In 1932, Bergmann et al. used carbobenzoxy-(Cbz) to protect the alpha - amino group, and the peptide synthesis had a certain development....
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23rd Apr 2018
Polypeptides are generally preserved in the form of freeze-dried powder, it is stable in -20℃, especially after freeze-dried and stored in the dryer. Most peptides can be stored at this temperature for several years unchangeably. If you use a sma...
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20th Apr 2018
There are two main ways to synthesize peptides: chemical synthesis and biosynthesis. Chemical synthesis is mainly achieved by the condensation reaction of amino acids. In order to get the synthetic polypeptide with specific sequence, when the amino a...
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19th Apr 2018
A common misconception about peptides is that peptides are as unstable as proteins. In fact, polypeptides are much more stable than proteins, because the two factors that affect the stability of proteins do not exist in polypeptide synthesis. Th...
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18th Apr 2018
What is the relationship between peptide and we humans? In the past few decades, the research of polypeptide has made great progress. Now scientists have made a clearer understanding of polypeptides. Scientists have found that peptides have a very im...
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17th Apr 2018
Peptide Synthesis
Symmetric Anhydride of Nα-alpha-acyl amino acid is an high-activity midbody for peptide bond formation. In contrast to the mixed anhydride method, it has no ambiguous regional selectivity with the reaction of the amine nucleophile...
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16th Apr 2018
Both organic carboxylic acid and inorganic acid can be used in the formation of acid anhydride. However, only a few have been widely applied, and in most cases, alkyl chloroformate is used. Ethyl chloroformate used in the past is mainly substituted b...
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13th Apr 2018
1. Inhibit cell degenerationPeptides can effectively inhibit cell degeneration and enhance human immunity, thus reducing the loss of collagen and improving skin relaxation.2. Activate cell activityBy activating cellular activity, peptides can effecti...
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13th Apr 2018
The formation of a peptide bond (which produces a dipeptide) is a simple chemical process on the surface. It refers to two amino acid components that are connected through the peptide bond (amide bond) and remove the water simultaneously.Under the co...
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